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Found 53 from The Hong Kong University of Science and Technology
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50:  6nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426919(CHEMBL2323707)
Affinity DataIC50:  9nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50:  15nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50:  29nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  32nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426917(CHEMBL2323709)
Affinity DataIC50:  37nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  43nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50199522((+)-huperzine A | (+-)-HA | (-)-1-Amino-13-ethylid...)
Affinity DataIC50:  65nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50:  66nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  147nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426918(CHEMBL2323708)
Affinity DataIC50:  187nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  237nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  249nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50:  347nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50:  401nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50:  503nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426914(CHEMBL2323712)
Affinity DataIC50:  530nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50:  574nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426922(CHEMBL2323704)
Affinity DataIC50:  590nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50:  893nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50:  1.36E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426916(CHEMBL2323710)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50:  2.41E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426915(CHEMBL2323711)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50:  2.76E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426921(CHEMBL2323705)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426926(CHEMBL2323716)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50:  6.36E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426925(CHEMBL2323717)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50:  7.66E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50:  8.07E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426924(CHEMBL2323718)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  8.72E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50:  8.98E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426923(CHEMBL2323703)
Affinity DataIC50:  9.67E+3nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50426928(CHEMBL2323714)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of AChE in Sprague-Dawley rat cortices using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
The Hong Kong University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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